Journal: Life
Article Title: Assessment of Alinity s Chagas ® as a Primary Diagnostic Test for Chronic Chagas Disease in a Non-Endemic Area of Europe (Barcelona, Spain)
doi: 10.3390/life14101278
Figure Lengend Snippet: Recombinant antigens with the antigenic domains used in the Architect Chagas and Alinity s Chagas assays (Abbott Laboratories, Wiesbaden, Germany) in comparison with BioELISA (Werfen, Lliçà d’Amunt, Spain) and VirClia (Vircell, Granada, Spain). Dark gray boxes represent the antigenic domains in BioELISA, light gray boxes the antigenic domains in Architect Chagas and Alinity s Chagas, and black boxes the antigenic domains in VirClia. Most antigenic domains are included in multi-domain recombinant antigens, which are indicated within the boxes for each serological assay (TcF, FP10, FP6, FP3, and MACH).
Article Snippet: Following its replacement of Architect Chagas in August 2020, the aim of the present study was to validate Alinity s Chagas ® , processed on the new Alinity s System ® (Abbott Laboratories, Wiesbaden, Germany), as a primary test for chronic CD diagnosis, applying an S/CO ratio ≥ 6.
Techniques: Recombinant, Comparison, Serologic Assay